Journal: Methods in molecular biology (Clifton, N.J.)

Article Title: A Method of Tumor In Vivo Imaging with a New Peptide-Based Fluorescent Probe

doi: 10.1007/978-1-0716-1811-0_45

Figure Lengend Snippet: The PDE neo® imaging system. (a) a schematic diagram of the NIR fluorescence imaging system. A real-time image is monitored and recorded by PC connected to the PDE neo® unit. (b) Photograph of the handhold NIR camera

Article Snippet: Real-Time NIR Monitoring System, PDE Neo (Mitaka USA Inc., Hamamatsu Photonics) Camera Unit list-behavior=enumerated prefix-word= mark-type=decimal max-label-size=0 Adjust the intensity of Excitation light.

Techniques: Imaging, Fluorescence

Journal: Methods in molecular biology (Clifton, N.J.)

Article Title: A Method of Tumor In Vivo Imaging with a New Peptide-Based Fluorescent Probe

doi: 10.1007/978-1-0716-1811-0_45

Figure Lengend Snippet: Real-time tumor imaging with the PDE neo® system coupled with ICG-p28. Human glioblastoma LN229 cells were injected s.c. into mice. Once tumors developed, ICG-p28 at 0.2 mg/kg body weight was injected i.v. into LN229 bearing athymic mice. After 24 h post-ICG-p28 injection, mice were imaged by the clinical PDE® system (Mitaka USA, Hamamatsu Photonics) with hand-held camera during tumor removal. Tumors were clearly identified through skin. Snapshot images of before (a) and after tumor resection (b) recorded by the PDE unit (dorsal view, 800 nm). Liver (green arrowhead) showed relatively high signal intensity as ICG excreted via liver. Red arrowheads: tumors

Article Snippet: Real-Time NIR Monitoring System, PDE Neo (Mitaka USA Inc., Hamamatsu Photonics) Camera Unit list-behavior=enumerated prefix-word= mark-type=decimal max-label-size=0 Adjust the intensity of Excitation light.

Techniques: Imaging, Injection

Journal: Operative Neurosurgery

Article Title: Near-Infrared Optical Contrast of Skull Base Tumors During Endoscopic Endonasal Surgery

doi: 10.1093/ons/opy213

Figure Lengend Snippet: Endoscope NIR demonstrates greater vignetting than white light. A, NIR intensity map overlaid on visible light view shows that NIR camera system using the endoscope demonstrates a focal light pattern toward the center of the ICG-enriched positive control medium. B, NIR-only view more clearly demarcates the concentric ring pattern as well as the focal light pattern toward the center. C, The distribution of white light from the endoscope is shown. D, The yellow lines from B and C show the slice that was used to calculate the intensity profile shown. Blue line shows the intensity profile for NIR-only view, and the black line shows the profile from the white light view.

Article Snippet: NIR Imaging Platform All cases were recorded using the FDA-approved VisionSense Iridium TM (Visionsense, Philadelphia, Pennsylvania), a 4-mm endoscope NIR camera system that utilizes dual optics for simultaneously imaging visible light and NIR views in real time.

Techniques: Positive Control